https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 The venous manifestations of pulse wave encephalopathy: windkessel dysfunction in normal aging and senile dementia https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4329 Wed 11 Apr 2018 16:27:34 AEST ]]> Arterial inflow and venous outflow in idiopathic intracranial hypertension associated with venous outflow stenoses https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4328 Wed 11 Apr 2018 16:04:47 AEST ]]> Emerging indications for magnetic resonance imaging in neuroradiology https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4536 Wed 11 Apr 2018 14:58:14 AEST ]]> An olfactory 'stress test' may detect preclinical Alzheimer's disease https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15148 Wed 11 Apr 2018 13:22:28 AEST ]]> Early detection of microstructural white matter changes associated with arterial pulsatility https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24721 Wed 11 Apr 2018 11:59:04 AEST ]]> Cerebrospinal fluid absorption block at the vertex in chronic hydrocephalus: obstructed arachnoid granulations or elevated venous pressure? https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16781 out). The CSF infusion studies measuring Rout are dependent on venous sinus pressure but little is known about the changes in pressure which occur throughout life or with the development of hydrocephalus. Methods: Twenty patients with chronic hydrocephalus underwent MR venography and MR flow quantification techniques. The venous outflow pressure was estimated from the sinus blood flow and the cross-sectional area of the transverse sinuses. Adult controls as well as a normal young cohort were selected to estimate the change in sinus pressure which occurs throughout life and following the development of hydrocephalus. Significance was tested with a Student’s t-test. Results: The size of the transverse sinuses was unchanged from the 1st to the 5th decade of life, indicating a stable outflow resistance. However, the blood flow was reduced by 42%, indicating a likely similar reduction in pressure gradient across the sinuses. The sinuses of hydrocephalus patients were 38% smaller than matched controls, indicating a 2.5 times increase in resistance. Despite the 24% reduction in blood flow, a significant increase in sinus pressure is suggested. Conclusions: The size of the venous sinuses normally does not change over the age range investigated but sinus pressure is reduced proportional to an age-related blood flow reduction. Hydrocephalus is associated with much smaller sinuses than normal and an elevation in venous pressure may explain the lack of CSF absorption into the arachnoid granulations in chronic hydrocephalus.]]> Wed 11 Apr 2018 09:46:05 AEST ]]> Dilatation of the bridging cerebral cortical veins in childhood hydrocephalus suggests a malfunction of venous impedance pumping https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52196 Wed 04 Oct 2023 15:07:38 AEDT ]]> Dilatation of the bridging cerebral veins in multiple sclerosis correlates with fatigue and suggests an increase in pressure https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50909 Tue 29 Aug 2023 11:01:27 AEST ]]> Comparison of the sagittal sinus cross-sectional area between patients with multiple sclerosis, hydrocephalus, intracranial hypertension and spontaneous intracranial hypotension: a surrogate marker of venous transmural pressure? https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33855 Tue 03 Sep 2019 18:30:25 AEST ]]> A comparison between the pathophysiology of multiple sclerosis and normal pressure hydrocephalus: is pulse wave encephalopathy a component of MS? https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26056 Thu 28 Oct 2021 12:37:14 AEDT ]]> Perfusion computed tomography: prediction of final infarct extent and stroke outcome https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:444 Thu 25 Jul 2013 09:09:49 AEST ]]> Chronic fatigue syndrome and multiple sclerosis have reduced craniospinal compliance and dilated pressurized bridging cortical veins https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54817 Thu 14 Mar 2024 14:45:39 AEDT ]]> The independent predictive utility of computed tomography angiographic collateral status in acute ischaemic stroke https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:8108 Sat 24 Mar 2018 08:40:00 AEDT ]]> A mathematical model of idiopathic intracranial hypertension incorporating increased arterial inflow and variable venous outflow collapsibility https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:8353 70% stenosis). In vivo measurements suggested a relative resistance elevation of 2.5 times normal, 4.2 times normal, and 4.8 times normal in the 3 groups, respectively. There was an increased inflow of 1.56 times normal, 1.28 times normal, and 1.19 times normal in these groups. Conclusions: The model correctly predicted the CSF pressures noted in vivo, suggesting that high arterial inflow is required for patients with low-grade stenoses to be symptomatic.]]> Sat 24 Mar 2018 08:39:52 AEDT ]]> Cerebral blood flow and hydrocephalus (letter) https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7258 Sat 24 Mar 2018 08:33:48 AEDT ]]> Perfusion computed tomography: prediction of final infarct extent and stroke outcome https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:1708 Sat 24 Mar 2018 08:27:38 AEDT ]]> External hydrocephalus in infants: six cases with MR venogram and flow quantification correlation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12223 Sat 24 Mar 2018 08:08:14 AEDT ]]> Hemodynamically significant venous collapse underlying neonatal hydrocephalus: clinical article https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21411 Sat 24 Mar 2018 08:05:01 AEDT ]]> Hypertensive slit ventricle syndrome: pseudotumor cerebri with a malfunctioning shunt? https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19988 Sat 24 Mar 2018 07:50:47 AEDT ]]> Pulse wave myelopathy: an update of an hypothesis highlighting the similarities between syringomyelia and normal pressure hydrocephalus https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26374 Sat 24 Mar 2018 07:33:07 AEDT ]]> Childhood hydrocephalus secondary to posterior fossa tumor is both an intra- and extraaxial process https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29845 Sat 24 Mar 2018 07:32:48 AEDT ]]> Stenoses in idiopathic intracranial hypertension: to stent or not to stent? (letter) https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4326 Sat 24 Mar 2018 07:18:23 AEDT ]]> A scoping review of the discrepancies in the measurement of cerebral blood flow in idiopathic intracranial hypertension: oligemia, euvolemia or hyperemia? https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51561 Mon 11 Sep 2023 09:34:50 AEST ]]> The dilated veins surrounding the cord in multiple sclerosis suggest elevated pressure and obstruction of the glymphatic system https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54939 Fri 22 Mar 2024 14:38:41 AEDT ]]> The dilated cortical veins found in multiple sclerosis can explain the reduction in glymphatic flow https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54938 Fri 22 Mar 2024 14:32:28 AEDT ]]> The measurement of CSF flow through the aqueduct in normal and hydrocephalic children: from where does it come, to where does it go? https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20374 Fri 14 Sep 2018 15:50:59 AEST ]]>